Reactions at the position

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Reactions at the $\alpha$ position

Halogenation (Hell-Volhard-Zelinski reaction aka HVZ)
- Bromine and phosphorus can react to form an $\alpha$ -halide carboxylic acid (aka $\alpha$ -halo acid):
  
  Figure 50.12: Carboxylic acid halogenation: The Hell-Volhard-Zelinski (HVZ) reaction. Halogenation occurs at the $\alpha$ -carbon of a carboxylic acid.
  $\includegraphics[width=5in]{img-o-carboxy_acid_HVZ_rxn.eps}$

**Figure 50.12:** Carboxylic acid halogenation: The Hell-Volhard-Zelinski (HVZ) reaction. Halogenation occurs at the $\alpha$ -carbon of a carboxylic acid.
$\includegraphics[width=5in]{img-o-carboxy_acid_HVZ_rxn.eps}$

Alfa Diallo 2006-08-04