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Carboxylic Acid Derivatives:
Acid Chlorides, Anhydrides,
Amides & Amines

What are four derivatives of carboxylic acids, i.e. acyl compounds?


The four acyl compounds (acid derivatives):

  1. Acyl chlorides (aka acid chlorides)
  2. Anhydrides
  3. Amides
  4. Esters



What are acyl chlorides?


Acyl chlorides are the most reactive derivatives of carboxylic acids, and they have a general molecular formula of $R-COCl$:

Figure 51.1: Acyl chloride.
\includegraphics{img-o-acyl_chloride.eps}

What are acid anhydrides?


The 2$^{nd}$ most reactive derivative of carboxylic acids which has a general molecular formula of $(RCO)_{2}O$:

Figure 51.2: Acyl anhydrides.
\includegraphics{img-o-acyl_anhydride.eps}

What are esters?


The 3$^{rd}$ most reactive derivative of carboxylic acids which has a general molecular formula of $RCO_{2}R'$ aka $RCOOR'$:

Figure 51.3: Esters.
\includegraphics{img-o-ester_2.eps}

What are amides?


The 4$^{th}$ most reactive derivative of carboxylic acids which has a general molecular formula of $R-CONH_{2}$:

Figure 51.4: Amides
\includegraphics{img-o-amide.eps}



Subsections
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Next: General Up: Organic Chemistry Previous: Reactions at the position   Contents
Alfa Diallo 2006-08-04